The Atomic Radius Of Fluoride (F) Is 147pm

The atomic radius of chloride is 175pm.Fluoride

Question

The atomic radius of fluoride (F-) is 147pm. The atomic radius of chloride is 175pm. Fluoride

coordinates four water molecules in aqueous media, and each coordination bond is worth 16kJ/mol. Chloride is able to coordinate six water molecules, with each bond having an energy of 12kJ/mol. In the GluClCh, chloride forms six coordination bonds with the protein channel worth 14kJ/mol each and fluoride forms 4 bonds with the protein channel worth 12kJ/mol each. What is the overall delta G for the desolvation of each ion in the channel? Why is the channel selective for chloride?

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